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Canagliflozin hemihydrate

Inquiry

Cat Number

API928672860

CAS Number

928672-86-0

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Product Detail

CAS Number

928672-86-0

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

JNJ28431754, TA 7284, TA7284, TA-7284, JNJ 28431754, JNJ-28431754

Description

Canagliflozin hemihydrate (TA 7284) is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%).

Molecular Formula

C48H52F2O11S2

Molecular Weight

907.05

Smiles

O[C@H]1[C@H](C2=CC(CC3=CC=C(C4=CC=C(C=C4)F)S3)=C(C=C2)C)O[C@@H]([C@H]([C@@H]1O)O)CO.O[C@H]5[C@H](C6=CC(CC7=CC=C(C8=CC=C(C=C8)F)S7)=C(C=C6)C)O[C@@H]([C@H]([C@@H]5O)O)CO.O

Purity

0.9996

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