Chlorotrianisene

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Cat Number

API569573

CAS Number

569-57-3

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Product Detail Description Customer Q&A

CAS Number

569-57-3

EINECS

209-318-6

Storage

Under -20℃

Synonyms

Chlorotris(4-methoxyphenyl)ethylene

Molecular Formula

C23H21ClO3

Molecular Weight

380.9

Smiles

COC1=CC=C(C=C1)C(=C(C2=CC=C(C=C2)OC)Cl)C3=CC=C(C=C3)OC

Appearance

Off-white solid

Melting Point

114-116℃

Boiling Point

496.07℃

Relative Density

1.1

General Description

Chlorotrianisene is a trianisylchloroethylene synthetic non-steroidal estrogen compound. It functions as a prodrug, undergoing slow metabolism in the liver to yield active estrogenic metabolites.

Mechanism of Action

Chlorotrianisene is stored in adipose tissue and slowly metabolized to active estrogenic compounds that bind and activate estrogen receptors, modulating transcription of estrogen-responsive genes in target tissues.

Application

Used in the treatment of estrogen deficiency conditions. Chlorotrianisene is indicated for menopausal vasomotor symptoms, atrophic vaginitis, ovarian failure, and prostate cancer palliation.

What distinguishes Chlorotrianisene from steroidal estrogens?

Chlorotrianisene is a non-steroidal synthetic estrogen that acts as a tissue reservoir, providing sustained slow-release estrogenic activity through gradual hepatic metabolism.