Boc-L-glutamic acid 5-cyclohexyl ester

Inquiry

Cat Number

INT73821973

CAS Number

73821-97-3

For research use only. We do not supply to patients.

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Product Detail Description Customer Q&A

CAS Number

73821-97-3

Storage

2-8℃

Synonyms

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-CYCLOHEXYL ESTER;N-BOC-L-GLUTAMIC ACID 5-CYCLOHEXYL ESTER;5-CYCLOHEXYL N-(TERT-BUTOXYCARBONYL)-L-GLUTAMATE

Molecular Formula

C16H27NO6

Molecular Weight

329.39

Smiles

N([C@@H](CCC(=O)OC1CCCCC1)C(=O)O)C(=O)OC(C)(C)C

Appearance

White to off-white solid

Melting Point

54-57℃

Boiling Point

502.6℃

Relative Density

1.16

pKa

3.79

General Description

Boc-L-glutamic acid 5-cyclohexyl ester is a protected L-glutamic acid derivative where the alpha-amine is Boc-protected and the gamma-carboxyl group is esterified with a cyclohexyl group. The cyclohexyl ester provides a unique balance of stability and hydrophobicity.

Mechanism of Action

It serves as a side-chain protected monomer. The cyclohexyl ester is stable to standard coupling conditions but can be removed to yield the free acid, allowing for the precise construction of glutamic acid-containing peptidomimetics with reduced side reactions.

Application

It is primarily used in the synthesis of specialized therapeutic peptides and as a tool in structural biology to study the role of acidic residues in protein folding and interaction.

How should Boc-L-glutamic acid 5-cyclohexyl ester be stored?

It should be kept in a cool area protected from moisture.

What is the purpose of the cyclohexyl ester?

The ester in it provides stable side-chain protection during synthesis.

Does it meet industry standards?

Yes, it is produced according to high international industry standards.

Are technical documents provided for it?

Yes, a batch-specific COA and SDS are provided with it.

Is global shipping available for it?

Yes, it is available for international delivery via secure logistics.

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