Description
Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity
Molecular Formula
C21H17F3N3NaO5
Smiles
O=C(C([O-])=C1C2=O)C(C(NCC3=C(F)C=C(F)C=C3F)=O)=CN1C[C@@H](O4)N2[C@@H]5C[C@H]4CC5.[Na+]
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: <1 mg/mL (insoluble or slightly soluble), Sonication and heating to 60℃ are recommended.