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Aprepitant

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Cat Number

API170729803

CAS Number

170729-80-3

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Product Detail

CAS Number

170729-80-3

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

MK-869, MK-0869, L-754030, Aprepitant

Description

Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.

Molecular Formula

C23H21F7N4O3

Molecular Weight

534.43

Smiles

C(N1[C@H]([C@@H](O[C@H](C)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)OCC1)C3=CC=C(F)C=C3)C4=NNC(=O)N4

Relative Density

1.51 (Predicted)

Standard

USP/CP/JP; Facility GMP

Qualification

USDMF/ASMF/JPMF/CEP/CDE

Purity

0.999

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