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Afatinib oxalate

Afatinib oxalate

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Cat Number
API1398312645
CAS Number
1398312-64-5

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CAS Number
1398312-64-5
Description
Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFRwt, 0.4 nM for EGFRL858R, 10 nM for EGFRL858R/T790M, and 14 nM for HER2. Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer.
Molecular Formula
C28H29ClFN5O11
Molecular Weight
666.01
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