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Afatinib oxalate

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Cat Number

API1398312645

CAS Number

1398312-64-5

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Product Detail

CAS Number

1398312-64-5

Description

Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFRwt, 0.4 nM for EGFRL858R, 10 nM for EGFRL858R/T790M, and 14 nM for HER2. Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer.

Molecular Formula

C28H29ClFN5O11

Molecular Weight

666.01

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