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5-Benzyl L-glutamate N-carboxyanhydride

5-Benzyl L-glutamate N-carboxyanhydride

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Cat Number
INT3190714
CAS Number
3190-71-4

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CAS Number
3190-71-4
Storage
Store at -20℃
Synonyms
H-GLU(OBZL)-NCA;Glutamic acid, 5-benzyl ester, NCA;Benzyl (S)-2,5-Dioxooxazolidine-4-propanoate;5-Benzyl Glutamic Acid Ester Nca
Molecular Formula
C13H13NO5
Molecular Weight
263.25
Smiles
O1C(=O)[C@H](CCC(OCC2=CC=CC=C2)=O)NC1=O
Appearance
White to off-white solid
Melting Point
97-98℃
Relative Density
1.29
pKa
9.03
General Description
5-Benzyl L-glutamate N-carboxyanhydride is the reactive NCA monomer of gamma-benzyl-L-glutamate, widely used to produce functionalized polyglutamates.
Mechanism of Action
It enables the synthesis of PBLG (Poly-gamma-benzyl-L-glutamate), a versatile polypeptide that can be further modified by removing the benzyl groups to form polyglutamic acid.
Application
It is primarily used in the creation of pH-responsive drug delivery vesicles and as a model system for studying protein secondary structures.

How should 5-Benzyl L-glutamate N-carboxyanhydride be stored?

It should be kept in a cool, dry place under an inert gas.

Is 5-Benzyl L-glutamate N-carboxyanhydride moisture sensitive?

Yes, it must be protected from humidity to prevent premature polymerization.

Does it meet industry standards?

Yes, its production is compliant with international industry standards.

Are COAs provided for 5-Benzyl L-glutamate N-carboxyanhydride?

Yes, a batch-specific COA is provided with it.

What is the role of 5-Benzyl L-glutamate N-carboxyanhydride?

It acts as a monomer for the synthesis of biocompatible polypeptides.
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