Z-ASP-OBZL

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Cat Number

INT4779311

CAS Number

4779-31-1

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Product Detail Description Customer Q&A

CAS Number

4779-31-1

Storage

2-8℃

Synonyms

Z-L-aspartic acid α-benzyl ester;CBZ-ASP-OBZL;N-Benzyloxycarbonyl-L-aspartic acid ALPHA-benzyl ester

Molecular Formula

C19H19NO6

Molecular Weight

357.36

Smiles

C(OCC1=CC=CC=C1)(=O)[C@H](CC(O)=O)NC(OCC1=CC=CC=C1)=O

Appearance

White to off-white solid

Melting Point

83-85℃

Boiling Point

583.5℃

Relative Density

1.29

pKa

4.09

General Description

Z-ASP-OBZL is a fully protected aspartic acid derivative with a benzyloxycarbonyl group at the amine and a benzyl ester at the alpha-carboxyl, leaving the side chain available for specific modifications.

Mechanism of Action

It functions as a selectively reactive intermediate. The benzyl-based protection allows for global deprotection in a single step using hydrogenation, or selective side-chain activation for branched peptide synthesis.

Application

It is primarily used in solution-phase peptide synthesis and in the construction of branched amino acid architectures for drug delivery.