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YXG-158

YXG-158

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Cat Number
API2952994340
CAS Number
2952994-34-0

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CAS Number
2952994-34-0
Description
YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1.28 μM and CYP17A1 inhibition with an IC50 of 100 nM. It is under investigation for potential use in research on enzalutamide-resistant prostate cancer.
Molecular Formula
C30H36FN3O
Molecular Weight
473.62
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