Xanthohumol

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Cat Number

PIPE-0506

CAS Number

6754-58-1

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Product Detail

CAS Number

6754-58-1

Storage

Room temperature

Synonyms

569-83-5 1-(2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one Xantho-flav

Description

Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as a metabolite, an apoptosis inducer, an antineoplastic agent, an antiviral agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor and an anti-HIV-1 agent. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-).

Molecular Formula

C21H22O5

Molecular Weight

354.4

Appearance

White Solid

Melting Point

157-159℃

Boiling Point

576.5±50.0 ℃ at 760 mmHg

Purity

HPLC≥98%