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Cat Number: API881681012

Vonoprazan FumarateTAK-438, TAK 438, Vonoprazan Fumurate, TAK438

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APIs
CAS Number
881681-01-2
Description
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19 nM at pH 6.5.
Molecular Formula
C21H20FN3O6S
Molecular Weight
461.46
Smiles
OC(=O)\C=C\C(O)=O.CNCC1CC(-C2CCCCC2F)N(C1)S(=O)(=O)C1CCCNC1
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Solubility Information
DMSO: 4.61 mg/mL (10 mM), Sonication is recommended.
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