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Vemurafenib

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Cat Number

API918504651

CAS Number

918504-65-1

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Product Detail

CAS Number

918504-65-1

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.

Molecular Formula

C23H18ClF2N3O3S

Molecular Weight

489.92

Smiles

C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F

Relative Density

1.46

Purity

0.9965

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