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Trimethoprim(TMP)

Trimethoprim(TMP)

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Cat Number
API738705
CAS Number
738-70-5

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CAS Number
738-70-5
EINECS
212-006-2
Synonyms
Proloprim Trimpex Trimetoprim
Description
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival.
Molecular Formula
C14H18N4O3
Molecular Weight
290.32
Appearance
odorless white powder
Melting Point
199-203 ℃
pKa
7.12 (at 20 ℃)
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