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Topotecan

Topotecan

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Cat Number
API123948878
CAS Number
123948-87-8

For research use only. We do not supply to patients.

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CAS Number
123948-87-8
EINECS
687-471-1
Synonyms
Topotecan lactone Hycamptamine Hycamptin
Description
Topotecan is a pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an antineoplastic agent.
Molecular Formula
C23H23N3O5
Molecular Weight
421.4
Appearance
Light Yellow to Yellow Solid
Melting Point
213-218 ℃
Boiling Point
782.9±60.0℃ at 760 mmHg
Standard
CP
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