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Topotecan

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Cat Number

API123948878

CAS Number

123948-87-8

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Product Detail

CAS Number

123948-87-8

EINECS

687-471-1

Synonyms

Topotecan lactone Hycamptamine Hycamptin

Description

Topotecan is a pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an antineoplastic agent.

Molecular Formula

C23H23N3O5

Molecular Weight

421.4

Appearance

Light Yellow to Yellow Solid

Melting Point

213-218 ℃

Boiling Point

782.9±60.0℃ at 760 mmHg

Standard

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