Tirzepatide

Description

Tirzepatide is composed of multiple amino acids and can simultaneously activate the Glucose-dependent Insulinotropic Polypeptide Receptor (GIPR) and the Glucagon-like Peptide-1 Receptor (GLP-1R).

Clinical Research Application

Type 2 diabetics

Tirzepatide regulates blood sugar levels glucose-dependently. In a state of high blood sugar, Tirzepatide enhances the sensitivity of pancreatic β cells to glucose; in a state of low blood sugar, Tirzepatide increases the release of glucagon, thereby maintaining an overall blood sugar balance.

Obesity

Because GIP and GLP-1 receptors are present in regions of the human brain that are important for appetite regulation, Tirzepatide, by activating these receptors, reduces hunger, decreases food intake, and can regulate energy balance.

Other potential applications

Research indicates that Tirzepatide may also have the potential to improve liver steatosis and reduce cardiovascular risk.

List of Commercial Drugs with Tirzepatide as Active Ingredient