TGF-β1

Human/Mouse/Rat

CHO Cells

CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1

Transforming growth factor-β1 (TGFb1) belongs to the TGF-β family with the highest percentage (>90%) and the most potent activity of a multifunctional regulator of cellular activity. Recombinant human transforming growth factor beta 1 (TGF-β1) is a biologically active protein used in cell culture applications.It is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types.The three mammalian isoforms of TGF-β1, TGF-β1, β2, and β3, signal through the same receptor and trigger similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation, and motility, as well as synthesis and deposition of extracellular matrix, and are involved in a variety of physiological processes, including embryogenesis, tissue remodeling, and wound healing. In stem cell culture, TGF-β1 is often used together with bFGF in the culture of undifferentiated human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells.

25kDa

liquid

> 95% as determined by SDS-PAGE.

Measured by the (CAGA)12—luciferase reporter assay. The EC50 for this effect is 1.092 ng/mL.

< 0.01 EU per 1μg of the protein by the LAL method.

In sterile PBS buffer, centrifuge the vial before opening it and the solution can be diluted into other aqueous buffers.

2, 10, 100μg