tert-butyl N-[(2S,3S)-2-(hydroxymethyl)-4-oxo-1-phenylmethoxyazetidin-3-yl]carbamate

tert-butyl N-[(2S,3S)-2-(hydroxymethyl)-4-oxo-1-phenylmethoxyazetidin-3-yl]carbamate

Cat Number
INT98377050
CAS Number
98377-05-0

If you have any other questions, please contact our experts.

CAS Number
98377-05-0
Molecular Formula
C16H22N2O5
Molecular Weight
322.36
Smiles
CC(C)(C)OC(=O)N[C@H]1[C@H](N(C1=O)OCC2=CC=CC=C2)CO
General Description
This compound is a polyfunctionalized azetidine derivative featuring a Boc-protected amine and a cyanomethyl group. carbamate]
Mechanism of Action
It functions as a protected building block for complex azetidine synthesis. The cyanomethyl group can be further reduced to an amine or hydrolyzed to an acid, providing versatile pathways for derivation.
Application
It is a key intermediate in the synthesis of Baricitinib, a Janus kinase (JAK) inhibitor used for treating rheumatoid arthritis and COVID-19.

How should tert-butyl N-[(2S,3S)-2-(hydroxymethyl)-4-oxo-1-phenylmethoxyazetidin-3-yl]carbamate be stored?

It should be kept in a cool, dry place in a sealed container.

What is its application?

It is used in the synthesis of Baricitinib.

Does it meet industry standards?

Yes, its production adheres to international standards for high-purity chemicals.

Are COAs provided?

Yes, every batch of it is supplied with a batch-specific COA.

Is global shipping available?

Yes, we ship it internationally in compliance with regulations.
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