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Cat Number: API202138509

Tenofovir Disoproxil Fumarate

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CAS Number

202138-50-9

Description

Tenofovir Disoproxil Fumarate is an acyclic phosphonate nucleotide analog and selective HIV-1 RT inhibitor.

Molecular Formula

C19H30N5O10P•C4H4O4

Molecular Weight

635.51

Smiles

C[C@H](CN1C=NC2=C1N=CN=C2N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=C/C(=O)O)\\C(=O)O

Storage

Store at 4℃

Melting Point

113-115℃

Boiling Point

642.7ºC at 760 mmHg

Optical Activity

n20D ~1.58

Flash Point

342.5ºC

Vapour Pressure

2.06E-16mmHg at 25℃

IC50

Human immunodeficiency virus 1: EC5050 = 2.9 nM; Human immunodeficiency virus 1: IC50 = 14 nM; HepG2: IC50 = 2.31 µM (human); Hepatitis B virus: IC50 = 5.1 µM

Solubility Information

Soluble in DMSO (128 mg/ml at 25℃), methanol, water

Relative Density

1.45

Standard

IP/CP; Facility GMP; Product GMP

Specification

An antiviral drug, is indicated as the treatment for both HIV and Hepatitis B virus[HBV]

Qualification

China DMF/USDMF/ASMF

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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