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Sunitinib

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Cat Number

API557795194

CAS Number

557795-19-4

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Product Detail

CAS Number

557795-19-4

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM). It exhibits antitumor activity and is used for treating kidney cancer and gastrointestinal tumors.

Molecular Formula

C22H27FN4O2

Molecular Weight

398.47

Smiles

C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3

Relative Density

1.229

Purity

0.9967

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