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Sunitinib Intermediate

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Cat Number

API56341414

CAS Number

56341-41-4

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Product Detail

CAS Number

56341-41-4

EINECS

638-803-9

Synonyms

5-Fluorooxindole 5-Fluoro-2-oxindole 5-fluoroindolin-2-one 5-fluoro-1,3-dihydroindol-2-one

Description

5-Fluoro-2-oxindole is an impurity of Sunitinib, which is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).

Molecular Formula

C8H6FNO

Molecular Weight

151.14

Appearance

Off-white to Beige Solid

Melting Point

143-144℃

Boiling Point

307.2±42.0℃ at 760 mmHg

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