APIs

Sulindac sulfidecis

Cat Number
API49627272
CAS Number
49627-27-2

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CAS Number
49627-27-2
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Description
Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 μM. It is an active metabolite of sulinic acid.
Molecular Formula
C20H17FO2S
Molecular Weight
340.41
Smiles
C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(SC)C=C3
Relative Density
1.3
Purity
0.9968
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