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Sorafenib tosylate

Inquiry

Cat Number

PIPE-0731

CAS Number

284461-73-0

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Product Detail

CAS Number

284461-73-0

EINECS

608-209-4

Storage

Room temperature

Synonyms

Nexavar BAY 43-9006 sorafenibum

Description

Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to treat renal carcinoma and differentiated thyroid carcinoma.

Molecular Formula

C21H16ClF3N4O3

Molecular Weight

464.8

Appearance

White solid

Melting Point

187-226

Purity

0.98

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