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Selumetinib

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Cat Number

API606143526

CAS Number

606143-52-6

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Product Detail

CAS Number

606143-52-6

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1).

Molecular Formula

C17H15BrClFN4O3

Molecular Weight

457.68

Smiles

CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO

Relative Density

1.69

Purity

0.9946

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