Safinamide

Inquiry

Cat Number

API133865891

CAS Number

133865-89-1

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Product Detail

CAS Number

133865-89-1

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

FCE-26743, EMD1195686, EMD 1195686

Description

Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson's disease, restless leg syndrome and epilepsy.

Molecular Formula

C17H19FN2O2

Molecular Weight

302.34

Smiles

O(CC1=CC(F)=CC=C1)C2=CC=C(CN[C@H](C(N)=O)C)C=C2

Relative Density

1.31

Purity

0.999

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