(S)-AMG-510

(S)-AMG-510

Cat Number
API2252403566
CAS Number
2252403-56-6

For research use only. We do not supply to patients.

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CAS Number
2252403-56-6
Storage
Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.
Description
(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C through covalent interaction with mutant cysteine, thereby promoting clinical efficacy in KRASG12C tumors.
Molecular Formula
C30H30F2N6O3
Molecular Weight
560.59
Smiles
O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C
Relative Density
1.36 (Predicted)
Purity
0.9857
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