Rhynchophylline

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Cat Number

PIPE-0620

CAS Number

76-66-4

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Product Detail

CAS Number

76-66-4

EINECS

683-092-0

Storage

Room temperature

Synonyms

Rhyncophylline Rhynchophyllin Mitrinermin

Description

Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and anticonvulsant activity of the Uncaira species plant extracts.Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, the present results suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

Molecular Formula

C22H28N2O4

Molecular Weight

384.5

Appearance

White cryst.

Melting Point

216 ℃

Boiling Point

560.8±50.0 ℃

Purity

0.98