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Pralsetinib

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Cat Number

API2097132948

CAS Number

2097132-94-8

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Product Detail

CAS Number

2097132-94-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion).

Molecular Formula

C27H32FN9O2

Molecular Weight

533.6

Smiles

CO[C@]1(CC[C@@H](CC1)C1NC(C)CC(NC2CC(C)[NH]N2)N1)C(=O)N[C@@H](C)C1CCC(NC1)-N1CC(F)CN1

Relative Density

1.40 (Predicted)

Purity

0.981

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