Ponatinib Hydrochloride

Inquiry

Cat Number

API1114544318

CAS Number

1114544-31-8

For research use only. We do not supply to patients.

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Product Detail

CAS Number

1114544-31-8

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

AP24534 Hydrochloride, AP 24534, AP-24534 Hydrochloride, Ponatinib hydrochloride

Description

Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

Molecular Formula

C29H28ClF3N6O

Molecular Weight

569.02

Smiles

Cl.CN1CCN(CC2CCC(NC(=O)C3CCC(C)C(C3)C#CC3CNC4CCCNN34)CC2C(F)(F)F)CC1

Standard

Facility GMP

Qualification

USDMF/HC MF

Purity

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