Polypropylene

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Cat Number

PIE-0154

CAS Number

9003-07-0

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Product Detail Description Scientific Support Customer Q&A

CAS Number

9003-07-0

Synonyms

PP Polypropylene

Molecular Formula

C22H42O3

Molecular Weight

354.57

Appearance

Translucent, white solid

Melting Point

157 ℃

Boiling Point

120-132 ℃

Relative Density

0.9

General Description

Polypropylene is a low-density, semi-crystalline thermoplastic resin with an outstanding combination of thermal, chemical, and electrical properties and with moderate strength. It is produced as molded powders, as extruded sheets, films, and fibers. Polypropylene has good resistance to strong acids, bases, and aqueous solutions of inorganic salts. It is a highly reliable, chemically inert material.

Application

Polypropylene is an important industrial manufacturing base resin for extrusion and injection molding for applications in packaging, textiles and structural components. In the pharmaceutical industry, this chemical inertness and low moisture permeability make polypropylene an important drug excipient and component of drug delivery devices.

A novel anti-adhesion polypropylene mesh for hernia repair, incorporating a poly(vinyl alcohol) (PVA) hydrogel barrier and rapamycin (RPM)-loaded liposomes (LPS). A PVA hydrogel coating was formed on PP mesh via green freezing–thawing cycles (FTP), and RPM-LPS was immobilized by swelling the lyophilized coating in liposome solution. The resulting RPM@LPS/PVA10-c-PP remained intact after 30 days in PBS at 37–40 ℃. In vitro assays confirmed good cytocompatibility and reduced cell adhesion. In a rat model, the modified mesh markedly decreased adhesion and elicited milder inflammation and looser fibrous encapsulation, as shown by histology.

Fig. 1 Polypropylene composite hernia mesh. (Wei D.; et al. 2023)

References

Wei D, et al. Polypropylene composite hernia mesh with anti-adhesion layer composed of PVA hydrogel and liposomes drug delivery system. Colloids and Surfaces B: Biointerfaces, 2023, 223: 113159.