Phloretin

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Cat Number

PIPE-0555

CAS Number

60-82-2

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Product Detail

CAS Number

60-82-2

EINECS

200-488-7

Storage

Room temperature

Synonyms

Dihydronaringenin 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one Phloretol

Description

Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences.

Molecular Formula

C15H14O5

Molecular Weight

274.27

Appearance

Pearl white powder

Melting Point

263.5 ℃

Boiling Point

534.4±29.0℃ at 760 Torr

Purity

HPLC≥98%