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Pemetrexed

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Cat Number

INT137281233

CAS Number

137281-23-3

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Product Detail Description

CAS Number

137281-23-3

EINECS

680-625-9

Synonyms

Pemetrexed disodium Alimta LY231514

Description

Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis.

Molecular Formula

C20H21N5O6

Molecular Weight

427.42

Application

Pemetrexed Disodium Intermediates

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