Synonyms
PDGF1, PDGF-A, PDGFAA, PDGF-AA
Description
PDGF is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. The A-chain homodimers of the platelet-derived growth factor (PDGF AA) are widely expressed in normal and transformed cells. The mitogenic properties of PDGF AA are well established. FGF-2 and platelet-derived growth factor-A (PDGF-AA) are potent modulators of oligodendrocytes, the main responsible cells for myelin regeneration.
Molecular Weight
Approximately 28.8 kDa.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
>95% by SDS-PAGE analyses.