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Pamiparib

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Cat Number

API1446261444

CAS Number

1446261-44-4

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Product Detail

CAS Number

1446261-44-4

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor with IC50 values of 0.9 nM for PARP1 and 0.5 nM for PARP2. It exhibits strong PARP trapping, has the capability to penetrate the brain, and is used for researching various cancers, including solid tumors.

Molecular Formula

C16H15FN4O

Molecular Weight

298.31

Smiles

C[C@]12CCCN1CC1N[NH]C(=O)C3CC(F)CC4[NH]C2C1C34

Relative Density

1.68 (Predicted)

Purity

0.9953

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