Oxprenolol Hydrochloride

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Cat Number

API6452739

CAS Number

6452-73-9

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Product Detail Description Customer Q&A

CAS Number

6452-73-9

EINECS

229-260-5

Storage

2-8℃

Synonyms

Oxprenolol HCl

Molecular Formula

C15H24ClNO3

Molecular Weight

301.81

Smiles

CC(C)NCC(COC1=CC=CC=C1OCC=C)O.Cl

Appearance

White to off-white solid

Melting Point

91-93℃

General Description

Oxprenolol Hydrochloride is a non-selective beta-adrenergic receptor blocker with intrinsic sympathomimetic activity of the aryloxypropanolamine class. It blocks both beta-1 and beta-2 receptors while partially activating them.

Mechanism of Action

Oxprenolol competes with endogenous catecholamines for beta-adrenergic receptor binding, reducing heart rate and myocardial contractility. Its intrinsic sympathomimetic activity provides partial receptor activation, preventing excessive bradycardia.

Application

Used in the treatment of cardiovascular disorders. Oxprenolol Hydrochloride is indicated for hypertension, angina pectoris, cardiac arrhythmias, and anxiety-related cardiovascular symptoms.

What advantage does intrinsic sympathomimetic activity provide?

ISA provides partial receptor activation during beta-blockade, reducing the risk of severe bradycardia and bronchospasm compared to beta-blockers without ISA.