N6-Carbobenzoxy-L-lysinine N-Carboxyanhydride

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Cat Number

INT1676864

CAS Number

1676-86-4

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CAS Number

1676-86-4

Storage

2-8℃

Synonyms

N-benzyloxycarbonyl-L-lysine N-carboxyanhydride

Molecular Formula

C15H18N2O5

Molecular Weight

306.31

Appearance

White to off-white solid

Melting Point

98-101℃

Relative Density

1.25

pKa

9.31

General Description

N6-Carbobenzoxy-L-lysinine N-Carboxyanhydride is a lysine-based NCA monomer featuring a Cbz-protected side chain, allowing for stable polymerization and versatile deprotection.

Mechanism of Action

It acts as a precursor for poly(epsilon-Cbz-L-lysine). The Cbz group provides excellent stability during polymerization and can be removed later via hydrogenolysis to reveal the free amino groups of the polylysine.

Application

It is a fundamental building block for the synthesis of functional polypeptides used in biosensor development and targeted therapeutic delivery.