N-Cbz-beta-alanine

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Cat Number

INT2304941

CAS Number

2304-94-1

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Product Detail Description Customer Q&A

CAS Number

2304-94-1

EINECS

218-967-4

Storage

2-8℃

Synonyms

carbobenzyloxy-beta-alanine;CBZ-BETA-ALANINE;CBZ-BETA-ALA-OH

Molecular Formula

C11H13NO4

Molecular Weight

223.23

Smiles

C1=CC=C(C=C1)COC(=O)NCCC(=O)O

Appearance

White solid

Melting Point

100-105℃

Boiling Point

435.9℃

Relative Density

1.25

pKa

4.45

General Description

N-Cbz-beta-alanine is a protected form of beta-alanine, an omega-amino acid, using the carbobenzyloxy (Z) group for amine protection.

Mechanism of Action

It serves as a non-alpha amino acid linker. The Cbz group is robust under basic conditions but can be easily removed via catalytic hydrogenation, allowing for flexible synthetic routes in solution or solid phase.

Application

It is widely used to introduce structural flexibility into peptide backbones and in the development of enzyme-resistant peptidomimetics.

How to store N-Cbz-beta-alanine?

It should be stored in a cool area protected from moisture.

Can the Cbz group in N-Cbz-beta-alanine be removed easily?

Yes, it is removed via standard hydrogenolysis conditions.

Does it follow international standards?

Yes, its production adheres to high international industry standards.

Are SDS provided for N-Cbz-beta-alanine?

Yes, a detailed SDS is provided for it with each order.

What is the application of N-Cbz-beta-alanine?

It is used for synthesizing peptidomimetics and molecular linkers.

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