N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide

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Cat Number

INT182182316

CAS Number

182182-31-6

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Product Detail Description Customer Q&A

CAS Number

182182-31-6

Storage

2-8℃

Synonyms

Acetamide, N-(8-amino-6-fluoro-1,2,3,4-tetrahydro-5-methyl-1-oxo-2-naphthalenyl)-;N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide hydrochloride

Molecular Formula

C13H15FN2O2

Molecular Weight

250.27

Smiles

C(NC1CCC2=C(C1=O)C(N)=CC(F)=C2C)(=O)C

Appearance

Off-white to gray solid

Relative Density

1.27

General Description

N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide is a highly functionalized tetrahydronaphthalene derivative, featuring an acetamide group, a ketone, and specifically positioned fluorine and methyl substituents. It represents a complex bicyclic scaffold used in medicinal chemistry.

Mechanism of Action

It functions as a rigid heterocyclic building block. The specific substitution pattern of the fluorine and methyl groups is designed to optimize electronic distribution and steric fit within biological receptor pockets, facilitating the creation of potent therapeutic agents.

Application

It is used as a critical intermediate for the synthesis of selective enzyme inhibitors and receptor modulators targeting various neurological or inflammatory pathways.

What is the role of fluorine in N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide?

The fluorine atom in it improves metabolic stability and target binding specificity.

Is N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide high purity?

Yes, it is produced to meet the high standards required for pharmaceutical intermediates.

How to store N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide?

It should be stored in a cool, dry, and dark environment to maintain its integrity.

Are COAs available for N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide?

Yes, every order of it includes a batch-specific Certificate of Analysis.

Is global shipping available for N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide?

Yes, we provide international logistics for it according to regulatory standards.

What is the main use of N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide?

It serves as a scaffold for developing selective enzyme inhibitors.