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Mevastatin/Compactin

Mevastatin/Compactin

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Cat Number
INT73573883
CAS Number
73573-88-3

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CAS Number
73573-88-3
EINECS
700-442-0
Synonyms
Compactin EC 700-442-0 Mevastatin ML-236B
Description
A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite and an apoptosis inducer.
Molecular Formula
C23H34O5
Molecular Weight
390.5
Appearance
White to Off-White Solid
Melting Point
152℃
Boiling Point
555.0±50.0 ℃ (Predicted)
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