LSN2839567

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Cat Number

API1231930576

CAS Number

1231930-57-6

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Product Detail

CAS Number

1231930-57-6

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Synonyms

Abemaciclib metabolite M2

Description

LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

Molecular Formula

C25H28F2N8

Molecular Weight

478.54

Smiles

CC(C)N1C(C)NC2C(F)CC(CC12)-C1NC(NC2CCC(CN3CCNCC3)CN2)NCC1F

Relative Density

1.38 (Predicted)

Purity

0.9914

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