Lomitapide

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Cat Number

API182431125

CAS Number

182431-12-5

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Product Detail

CAS Number

182431-12-5

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Description

Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.

Molecular Formula

C39H37F6N3O2

Molecular Weight

693.72

Smiles

FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C2CCCCC2-C2CCC(CC2)C(F)(F)F)C2CCCCC2-C2CCCCC12

Relative Density

1.34 (Predicted)

Purity

0.9977

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