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Cat Number: API103577453

LansoprazoleA-65006, AG-1749

CAS Number

103577-45-3

Description

Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)

Molecular Formula

C16H14F3N3O2S

Molecular Weight

369.36

Smiles

CC1=C(CS(=O)C2=NC3=CC=CC=C3N2)N=CC=C1OCC(F)(F)F

Purity

0.9984

Storage

Powder: -20℃ for 3 years. In solvent: -80℃ for 1 year.

Solubility Information

1eq. HCl: 18.5 mg/mL (50 mM)DMSO: 50 mg/mL (135.37 mM)