Synonyms
IRINOTECAN HYDROCHLORIDE Trihydrate
Camptosar
Irinotecan Hcl Trihydrate
Campto
Description
A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
Molecular Formula
C33H45ClN4O9
Appearance
Pale yellow to yellow crystalline solid
Melting Point
>245℃ (dec.)