Cat Number: 91212ES

IFN-γ-3

Source

E.coli

Synonyms

Interferon-gamma, IFN-γ, IFG, IFI, IFNG, IFNgamma, IFN-gamma.

Description

Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a pleiotropic cytokine which is now recognised as an important modulator of the immune response. Mature human IFN-γ exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits.

Molecular Weight

Approximately 15.5 kDa.

AA sequence

HGTVIESLES LNNYFNSSGI DVEEKSLFLD IWRNWQKDGD MKILQSQIIS FYLRLFEVLK DNQAISNNIS VIESHLITTF FSNSKAKKDA FMSIAKFEVN NPQVQRQAFN ELIRVVHQLL PESSLRKRKR SRC

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 96%，SDA-PAGE

Biological Activity

The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.8 ng/ml, corresponding to a specific activity of > 1.3 × 106 IU/mg. Fully biologically active when compared to standard.

Endotoxin

<1.0 EU/μg

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4

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