High-Substituted Hydroxypropyl cellulose

Hydroxypropyl cellulose is a non-ionic cellulose ether obtained by the reaction of alkaline cellulose and propylene oxide under high temperature and high pressure. L-HPC) and highly substituted hydroxypropyl cellulose (H-HPC). L-HPC has a low degree of hydroxypropyl substitution, typically between 9% and 15%. In contrast, HPC has a higher degree of hydroxypropyl substitution, usually around 60%. This different degree of hydroxypropyl substitution affects the properties of the two species. For example, L-HPC has good flowability and compressibility, so it is often used as a disintegrant and binder for pharmaceutical tablets. On the other hand, HPC has good solubility and viscosity, so it is often used as a thickener, emulsifier and film former.