H2N-PEG2-CH2COOH / (H-AEEA-OH)

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Cat Number

INT134978975

CAS Number

134978-97-5

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Product Detail

CAS Number

134978-97-5

EINECS

810-220-6

Synonyms

2-(2-(2-Aminoethoxy)ethoxy)acetic acid 2-[2-(2-aminoethoxy)ethoxy]acetic acid 8-Amino-3,6-dioxaoctanoic acid H2N-PEG2-CH2COOH

Description

H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Molecular Formula

C6H13NO4

Molecular Weight

163.17

Appearance

White Powder

Boiling Point

323.8 ℃ at 760 mmHg

Applications

Semaglutide intermediate

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