Synonyms
Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin
Description
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive.
Molecular Weight
Approximately 18.9 kDa
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 98% by SDS-PAGE and HPLC analyses.