FMOC-MENVA-OH

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Cat Number

INT252049051

CAS Number

252049-05-1

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Product Detail Description Customer Q&A

CAS Number

252049-05-1

Storage

2-8℃

Synonyms

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-L-NORVALINE

Molecular Formula

C21H23NO4

Molecular Weight

353.41

Smiles

CCC[C@@H](C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Appearance

White to off-white solid

Melting Point

130.0 to 135.0℃

Boiling Point

533.1℃

pKa

3.92

General Description

FMOC-MENVA-OH is an Fmoc-protected version of N-methyl-L-norvaline, a non-proteinogenic amino acid featuring a linear five-carbon side chain.

Mechanism of Action

It acts as a hydrophobic building block. The combination of the norvaline side chain and the N-methyl group creates a unique steric and lipophilic profile that can be used to probe the hydrophobic pockets of receptors.

Application

It is primarily used in the development of specialized peptide libraries and as a tool for studying protein-ligand interactions in medicinal chemistry.