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FMOC-ASP(OCHEX)-OH

FMOC-ASP(OCHEX)-OH

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Cat Number
INT130304802
CAS Number
130304-80-2

If you have any other questions, please contact our experts.

CAS Number
130304-80-2
Storage
2-8℃
Synonyms
FMOC-L-ASPARATIC ACID-BETA-CYCLOHEXYL ESTER;FMOC-L-ASPARTIC ACID BETA-CYCLOHEXYL ESTER
Molecular Formula
C25H27NO6
Molecular Weight
437.48
Smiles
C1CCC(CC1)OC(=O)C[C@@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Appearance
White to off-white solid
Boiling Point
667.8℃
Relative Density
1.31
pKa
3.55
General Description
FMOC-ASP(OCHEX)-OH is a side-chain protected aspartic acid derivative where the carboxyl group is masked as a cyclohexyl ester. This specific protection reduces side reactions such as aspartimide formation.
Mechanism of Action
It acts as a sterically hindered building block. The cyclohexyl ester (OChx) provides better stability compared to simpler esters, minimizing unwanted cyclization during chain elongation in solid-phase synthesis.
Application
It is a premium choice for the synthesis of complex peptides containing aspartic acid sequences where high purity and minimal by-products are critical.

What is the benefit of the OChx group in FMOC-ASP(OCHEX)-OH?

It significantly reduces the risk of aspartimide formation during the synthesis of it.

How should FMOC-ASP(OCHEX)-OH be stored?

It should be kept in a cool, dry place in a sealed container.

Does it meet industry standards?

Yes, its production is compliant with international industry standards.

Are COAs available for FMOC-ASP(OCHEX)-OH?

Yes, we provide a batch-specific COA for it with every shipment.

Is FMOC-ASP(OCHEX)-OH stable during shipping?

Yes, it is stable and handled according to professional laboratory protocols.
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