FMOC-5-AMINOPENTANOIC ACID

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Cat Number

INT123622480

CAS Number

123622-48-0

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Product Detail Description Customer Q&A

CAS Number

123622-48-0

Storage

2-8℃

Synonyms

FMOC-NH-(CH2)4-COOH;FMOC-APE(5)-OH

Molecular Formula

C20H21NO4

Molecular Weight

339.39

Smiles

C(O)(=O)CCCCNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

Appearance

White powder

Melting Point

135-136℃

Boiling Point

575.8℃

Relative Density

1.23

pKa

4.71

General Description

FMOC-5-AMINOPENTANOIC ACID is an Fmoc-protected omega-amino acid featuring a five-carbon alkyl chain. It is commonly used as a flexible linker or spacer in bioconjugation and peptide chemistry.

Mechanism of Action

It acts as a flexible molecular bridge. The Fmoc group allows for its incorporation into peptide chains using standard coupling methods, providing a defined distance between functional moieties without introducing chiral centers.

Application

It is widely used for linking dyes, biotin, or drugs to peptides and proteins, as well as for increasing the solubility and flexibility of synthetic peptide constructs.