General Description
Fluoxymesterone is a synthetic androgenic steroid with a 9α-fluoro and 11β-hydroxy substitution, belonging to the class of anabolic-androgenic steroids. Its chemical structure is 9α-fluoro-11β,17β-dihydroxy-17α-methyl-4-androsten-3-one. Fluoxymesterone is a white to off-white crystalline powder, practically insoluble in water but soluble in organic solvents. It is a potent androgen with both anabolic and androgenic effects.
Mechanism of Action
Fluoxymesterone binds to the androgen receptor in target tissues, promoting protein synthesis, muscle growth, and the development of male secondary sex characteristics. It also suppresses gonadotropin secretion through negative feedback, reducing testosterone production.
Application
Fluoxymesterone is indicated for the treatment of male hypogonadism, delayed puberty, and for the palliation of certain breast cancers in women. It is also used for the treatment of osteoporosis and for the management of the symptoms of androgen deficiency.