Fluoxymesterone

Fluoxymesterone

Cat Number
API0232296
CAS Number
76-43-7

For research use only. We do not supply to patients.

For pharmaceutical-grade products or other inquiries, please contact our experts.

CAS Number
76-43-7
EINECS
200-961-8
Storage
Store at room temperature
Synonyms
Halotestin; Androfluorene; Androfluorone; Fluoximesterone; Fluotestin
Molecular Formula
C20H29FO3
Molecular Weight
336.4
Smiles
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@]4(C)O)C)O)F
Appearance
White to light yellow crystalline powder
Melting Point
240°C
Boiling Point
474.2±45.0°C at 760 mmHg
Relative Density
1.0455 (Estimate)
General Description
Fluoxymesterone is a synthetic androgenic steroid with a 9α-fluoro and 11β-hydroxy substitution, belonging to the class of anabolic-androgenic steroids. Its chemical structure is 9α-fluoro-11β,17β-dihydroxy-17α-methyl-4-androsten-3-one. Fluoxymesterone is a white to off-white crystalline powder, practically insoluble in water but soluble in organic solvents. It is a potent androgen with both anabolic and androgenic effects.
Mechanism of Action
Fluoxymesterone binds to the androgen receptor in target tissues, promoting protein synthesis, muscle growth, and the development of male secondary sex characteristics. It also suppresses gonadotropin secretion through negative feedback, reducing testosterone production.
Application
Fluoxymesterone is indicated for the treatment of male hypogonadism, delayed puberty, and for the palliation of certain breast cancers in women. It is also used for the treatment of osteoporosis and for the management of the symptoms of androgen deficiency.

Does Fluoxymesterone require protection from light during long‑term storage?

Yes, it is photosensitive. UV exposure can cause photodegradation and discoloration of the steroid ring. Store in light‑resistant containers, preferably amber glass.

What is the recommended storage temperature for Fluoxymesterone?

Store at controlled room temperature (15–25°C). Avoid excessive heat above 30°C, which can soften the powder and accelerate oxidation.

Is Fluoxymesterone stable in tablet formulations with standard excipients?

Yes, when formulated with standard excipients and protected from moisture.

How is the impurity fluoxymesterone 11β‑hydroxy (a process‑related impurity) monitored?

This impurity is quantified using a stability‑indicating HPLC method, ensuring it remains within pharmacopoeial limits.
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